Central Americans who migrate often seek safer, more productive lives. Meanwhile, an increasing number of migrants from other Latin American and Caribbean countries are crossing Central America with that same hope. And the influx of migrants who return to Central America after undergoing often traumatic migration experiences is also on the rise. This panel will unpack the evident, yet complex nexus between fragility and human mobility in Central America. The panel will reflect on the growing body of evidence on the factors of fragility and instability (e.g., violence, climate change, weak rule of law and local governance, democratic backsliding) that prevent Central Americans from unleashing their potential and fuel irregular, perilous migration. The panel will discuss viable pathways to resiliency in home/host communities in Central America and to enable effective migrant (re)integration, building on the comprehensive framework for migrant-centered responses to fragility and stability laid out in the U.S. Strategy for Addressing the Root Causes of Irregular Migration from Central America and the Los Angeles Declaration on Migration and Protection.